This paper examines farmer intentions to adapt to global climate change by analyzing responses to a climate change scenario presented in a survey given to large-scale farmers across the US Corn Belt in 2012. Adaptive strategies are evaluated in the context of decision making and farmers’ intention to increase their use of three production practices promoted across the Corn Belt: no-till farming, cover crops, and tile drainage. This paper also provides a novel conceptual framework that bridges a typology of adaptation (...) with concepts that help predict intentionality in behavior change models. This conceptual framework was developed to facilitate examination of adaptive decision making in the context of agriculture. This research effort examines key factors that influence farmers’ intentions to increase their use of the practices evaluated given a climate change scenario. Twenty-two covariates are examined across three models developed for no-till farming, cover crops, and tile drainage. Findings highlight that farmers who believed they should adjust their practices to protect their farm from the negative impacts of increased weather variability were more likely to indicate that they would increase their use of each of the practices in response to climate change. Additionally, visiting with other farmers to observe their practices was positively associated with farmers’ intentions to increase their use of the adaptive strategies examined. Farmers who were currently using no-till farming, cover crops, and tile drainage were also more likely to plan to increase their use of these practices in response to increased weather variability associated with climate change. However, farmers who reported high levels of confidence in their current practices were less likely to plan on changing their use of these practices in response to climatic changes. (shrink)

This paper examines the consequences of a culture of “personal ethics” when using new methodologies, such as the use of social media sites as a source of data for research. Using SM research as an example, this paper explores the practices of a number of actors and researchers within the “Ethics Ecosystem” which as a network governs ethically responsible research behaviour. In the case of SM research, the ethical use of this data is currently in dispute, as even though it (...) is seemingly publically available, concerns relating to privacy, vulnerability, potential harm and consent blur the lines of responsible ethical research behaviour. The findings point to the dominance of a personal, bottom-up, researcher-led, ‘ethical barometer’ for making decisions regarding the permissibility of using SM data. We show that the use of different barometers by different researchers can lead to wide disparities in ethical practice - disparities which are compounded by the lack of firm guidelines for responsible practice of SM research. This has widespread consequences on the development of shared norms and understandings at all levels, and by all actors within the Ethics Ecosystem, and risks inconsistencies in their approaches to ethical decision-making. This paper argues that this governance of ethical behaviour by individual researchers perpetuates a negative cycle of academic practice that is dependent on subjective judgements by researchers themselves, rather than governed by more formalised academic institutions such as the research ethics committee and funding council guidelines. (shrink)

Gene drives are selfish genetic elements that use a variety of mechanisms to ensure they are transmitted to subsequent generations at greater than expected frequencies. Synthetic gene drives based on the clustered regularly interspersed palindromic repeats genome editing system have been proposed as a way to alter the genetic characteristics of natural populations of organisms relevant to the goals of public health, conservation, and agriculture. Here, we review the principles and potential applications of CRISPR drives, as well as means proposed (...) to prevent their uncontrolled spread. We also focus on recent work suggesting that factors such as natural genetic variation and inbreeding may represent substantial impediments to the propagation of CRISPR drives. CRISPR-based synthetic selfish genetic elements, or gene drives, have been proposed as a means by which to genetically alter natural populations to address issues in agriculture, conservation, and public health. We describe key concepts of CRISPR gene drives and limitations that must be addressed before their use in the wild. (shrink)

This paper describes a novel method for the delivery of an introductory module on survey sampling at a third?level institution. As part of the module, students undertake a practical survey that is of interest not only to themselves but also to university administrators and other module coordinators. Unlike many data collection activities used in class, these data have intrinsic value. This module is shown to produce students with a high level of expertise in survey sampling. It also fosters in students (...) wider generic capacities, such as information, communication and problem?solving skills and teamwork and leadership skills that prepare them for further study and employment. The emphasis on activity?based learning has led to increased student participation, improved examination results as well as enhanced student satisfaction with the module. (shrink)

Classification learning is a preeminent human ability within the animal kingdom but the key mechanisms of brain networks regulating learning remain mostly elusive. Recent neuroimaging advancements have depicted human brain as a complex graph machinery where brain regions are nodes and coherent activities among them represent the functional connections. While long-term motor memories have been found to alter functional connectivity in the resting human brain, a graph topological investigation of the short-time effects of learning are still not widely investigated. For (...) instance, classification learning is known to orchestrate rapid modulation of diverse memory systems like short-term and visual working memories but how the brain functional connectome accommodates such modulations is unclear. We used publicly available repositories (openfmri.org) selecting three experiments, two focused on short-term classification learning along two consecutive runs where learning was promoted by trial-by-trial feedback errors, while a further experiment was used as supplementary control. We analyzed the functional connectivity extracted from BOLD fMRI signals, and estimated the graph information processing in the cerebral networks. The information processing capability, characterized by complex network statistics, significantly improved over runs, together with the subject classification accuracy. Instead, null-learning experiments, where feedbacks came with poor consistency, did not provoke any significant change in the functional connectivity over runs. We propose that learning induces fast modifications in the overall brain network dynamics, definitely ameliorating the short-term potential of the brain to process and integrate information, a dynamic consistently orchestrated by modulations of the functional connections among specific brain regions. (shrink)

This volume consists of fourteen chapters selected from papers presented at the conference 'Ethics, Medicine and Health Care: An Appraisal of the Thought of H. Tristram Engelhardt, Jr.' along with a response to those chapters by Engelhardt and a Foreword by Laurence B. McCullough. The chapters direct primary attention to various aspects of Engelhardt's philosophy of medicine and bioethics as presented in The Foundations of Bioethics and Bioethics and Secular Humanism: The Search for a Common Morality. Among the topics treated (...) are the economics of health care and the medical profession, the libertarian and communitarian aspects of Engelhardt's thought, the moral status of children, abortion, the moral foundations for a health care system, feminism and clinical epistemology, and the relation between secular and religious moralities. In response to the various challenges posed by the authors, Engelhardt considers the implications of the failure of the modern philosophical project, the role of reason in ethics, and the resolution of conflict among communities that do not share the same moral vision. The book will be of interest to professionals in medicine, philosophy, theology, health policy, and law, and to graduate students in those disciplines. (shrink)

Open peer commentary on the article “Exploring the Depth of Dream Experience: The Enactive Framework and Methods for Neurophenomenological Research” by Elizaveta Solomonova & Xin Wei Sha. Upshot: Solomonova and Sha draw inspiration from the work programme that sparked the enactive extension to cognitive science, and propose a framework for dream scientists. This case study for a renewed cognitive science highlights key points that are worth developing, in light of current practices in neuroscience.

Upshot: Albeit mostly supportive of our work, the commentaries we received highlighted a few points that deserve additional explanation, with regard to the notion of learning in our model, the relationship between our model and the brain, as well as the notion of anticipation. This open discussion emphasizes the need for toy computer models, to fuel theoretical discussion and prevent business-as-usual from getting in the way of new ideas.

Context: Constructivist approaches to cognition have mostly been descriptive, and now face the challenge of specifying the mechanisms that may support the acquisition of knowledge. Departing from cognitivism, however, requires the development of a new functional framework that will support causal, powerful and goal-directed behavior in the context of the interaction between the organism and the environment. Problem: The properties affecting the computational power of this interaction are, however, unclear, and may include partial information from the environment, exploration, distributed processing (...) and aggregation of information, emergence of knowledge and directedness towards relevant information. Method: We posit that one path towards such a framework may be grounded in these properties, supported by dynamical systems. To assess this hypothesis, we describe computational models inspired from swarm intelligence, which we use as a metaphor to explore the practical implications of the properties highlighted. Results: Our results demonstrate that these properties may serve as the basis for complex operations, yielding the elaboration of knowledge and goal-directed behavior. Implications: This work highlights aspects of interaction that we believe ought to be taken into account when characterizing the possible mechanisms underlying cognition. The scope of the models we describe cannot go beyond that of a metaphor, however, and future work, theoretical and experimental, is required for further insight into the functional role of interaction with the environment for the elaboration of complex behavior. Constructivist content: Inspiration for this work stems from the constructivist impetus to account for knowledge acquisition based on interaction. (shrink)

En esta primera parte de la entrevista, Mignolo ubica las coordenadas intelectuales en las que surge su primera obra (1995) junto con la necesidad del desarrollo del concepto de semiosis colonial, y la recepción de sus tesis en aquel momento. Describe también las posibilidades (o imposibilidades) de diálogo de la perspectiva decolonial con otras como la posmoderna y la poscolonial, refiriéndose a las diferentes inscripciones teóricas debidas, fundamentalmente, a diferencias geopolíticas. Por ello, plantea una alternativa pluri-versal al universalismo moderno occidental, (...) que intenta hacer pasar su provincialismo, cristiano primero, luego liberal y ahora neoliberal, por la verdad misma (eurocentrismo o atlanticismo). Finalmente, sitúa su “conformación cosmo-cultural” en relación con la reconstitución de conceptos que la civilización occidental fue destituyendo en su proceso de constitución del vocabulario y las subjetividades moderno-coloniales. Grupo de estudio Las nociones de transmodernidad y pluriversidad en la Filosofía de la Liberación y el giro decolonial. (shrink)

Humans, animals, and the environment face a universal crisis: antimicrobial resistance. Addressing AR and its multi-disciplinary causes across many sectors including in human and veterinary medicine remains underdeveloped. One barrier to AR efforts is an inconsistent process to incorporate the plenitude of stakeholders about what AR is and how to stifle its development and spread—especially stakeholders from the animal agriculture sector, one of the largest purchasers of antimicrobial drugs. In 2019, The Wellcome Trust released Reframing Resistance: How to communicate about (...) antimicrobial resistance effectively, which proposed the need to establish a consistent and harmonized messaging effort that describes the AR crisis and its global implications for health and wellbeing across all stakeholders. Yet, Reframing Resistance does not specifically engage the animal agriculture community. This study investigates the gap between two principles recommended by Reframing Resistance and animal agriculture stakeholders. For this analysis, the research group conducted 31 semi-structured interviews with a diverse group of United States animal agriculture stakeholders. Participants reported attitudes, beliefs, and practices about a variety of issues, including how they defined AR and what entities the AR crisis impacts most. Exploration of Reframing Resistance’s Principle 2, “explain the fundamentals succinctly” and Principle 3, “emphasis that this is universal issue; it can affect anyone, including you” reveals disagreement in both the fundamentals of AR and consensus of “who” the AR crisis impacts. Principle 2 may do better to acknowledge that animal agriculture stakeholders espouse a complex array of perspectives that cannot be summed up in a single perspective or principle. As a primary tool to combat AR, behavior change must be accomplished first through outreach to stakeholder groups and understanding their perspectives. (shrink)

Bullfighting has a strong historical tradition in Spain, but now it is beginning to be challenged by various sectors in society. The debate about the ethics of bullfighting is by no means new. But,...

Biological and epidemiological phenomena are often measured with error or imperfectly captured in data. When the true state of this imperfect measure is a confounder of an outcome exposure relationship of interest, it was previously widely believed that adjustment for the mismeasured observed variables provides a less biased estimate of the true average causal effect than not adjusting. However, this is not always the case and depends on both the nature of the measurement and confounding. We describe two sets of (...) conditions under which adjusting for a non-deferentially mismeasured proxy comes closer to the unidentifiable true average causal effect than the unadjusted or crude estimate. The first set of conditions apply when the exposure is discrete or continuous and the confounder is ordinal, and the expectation of the outcome is monotonic in the confounder for both treatment levels contrasted. The second set of conditions apply when the exposure and the confounder are categorical. In all settings, the mismeasurement must be non-differential, as differential mismeasurement, particularly an unknown pattern, can cause unpredictable results. (shrink)

This article focuses on what bodies know yet which cannot be expressed verbally. We started with a problem encountered during conventional interviewing in an ex-mining community in south Wales when some teen girls struggled to speak. This led us to focus on the body, corporeality and movement in improvisational dance workshops. By slowing down and speeding up video footage from the workshops, we notice movement patterns and speculate about how traces of gender body-movement practices developed within mining communities over time (...) become actualised in girls’ habitual movement repertoires. Inspired by the works of Gilles Deleuze, Felix Guattari and Erin Manning, a series of cameos are presented: room dancing; the hold; the wiggle; the leap and the dance of the not-yet. We speculate about relations between the actual movements we could see, the in-act infused with the history of place, and the virtual potential of movement. (shrink)

Among semanticists and philosophers of language, there has been a recent outburst of interest in predicates such as delicious, called predicates of personal taste (PPTs, e.g. Lasersohn 2005). Somewhat surprisingly, the question of whether or how we can distinguish aesthetic predicates from PPTs has hardly been addressed at all in this recent work. It is precisely this question that we address. We investigate linguistic criteria that we argue can be used to delineate the class of specifically aesthetic adjectives. We show (...) that there are, in fact, good motivations for keeping PPTs and aesthetic predicates apart: the semantic structure of the former, but not the latter, entails an experiencer. There are many adjectives whose semantic structure arguably also entails an experiencer, yet which are readily used in expressing aesthetic judgments. Adjectives such as provocative or moving are a case in point, since as adjectives they arguably maintain the experiencer argument from the verb they are derived from. Nevertheless, when we describe, say, a sculpture as provocative, or a theater performance as moving, we clearly make aesthetic judgments. The difficult question, then, is to articulate the relationship between an aesthetic predicate (of which beautiful and ugly are paradigms) and other predicates that just happen to be used in making an aesthetic judgment. Tightly related to this point is the more general question of the relationship between an evaluative predicate and a predicate that occurs in an evaluative judgment. One of our aims is to make some progress in addressing these questions. (shrink)

En este trabajo nos proponemos realizar una aproximación a las estrategias de transmisión del pasado reciente en el Espacio Mansión Seré (EMS), ubicado dentro del polideportivo municipal Gorki-Grana, en el Municipio de Morón, provincia de Buenos Aires. Dicho espacio constituye una referencia de importancia en lo que hace a las políticas públicas sobre derechos humanos y memoria tanto a nivel provincial como nacional. En esta aproximación, nos interesa indagar en algunos de los modos en que la investigación arqueo-antropológica es utilizada (...) para construir un relato y una narrativa sobre la historia del lugar. Centrándonos en el período 2013-2016, el foco estará puesto en cómo esta narrativa se materializa a través de los modos en que los testimonios, objetos y fotografías del archivo documental se articulan, se traman y dialogan entre sí en el espacio y en el recorrido del EMS. La hipótesis es que, haciendo uso de las huellas del pasado, en diferentes dispositivos instalados en el espacio se intenta propiciar la imaginación como medio para la reflexión sobre la historia del lugar. (shrink)

The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A (...) smaller majority reported changes in personality specifically. Some expressed reservations about the scientific status of the term ‘personality,’ while others used it freely. Most researchers discussed negative PMB changes, but a majority said that DBS/aDBS can also result in positive changes. Several researchers viewed positive PMB changes as part of the therapeutic goal in psychiatric applications of DBS/aDBS. Finally, several discussed potential causes of PMB changes other than the device itself. (shrink)

The Walmart Company is one of the favorite punching bags of market critics. They accuse this firm of underpaying employees, dealing unfairly with customers, exploiting suppliers, and bankrupting small competitors. Various political jurisdictions have banned this firm from their environs, either implicitly or explicitly. The present article offers a more nuanced position on the behemoth from Arkansas. Although it has some flaws, there is an overwhelming case to be made in its behalf as an employer, competitor, purchaser, benefactor of customers.

In April 1939, G. E. Moore read a paper to the Cambridge University Moral Science Club entitled ‘Certainty’. In it, amongst other things, Moore made the claims that: the phrase ‘it is certain’ could be used with sense-experience-statements, such as ‘I have a pain’, to make statements such as ‘It is certain that I have a pain’; and that sense-experience-statements can be said to be certain in the same sense as some material-thing-statements can be — namely in the sense that (...) they can be safely counted on. When Moore later read his paper to Wittgenstein, Wittgenstein took violent exception to it, and the two entered into a heated exchange. The only known notes of this exchange are a previously unpublished verbatim record of part of it, taken by Norman Malcolm. This paper is an edition of Malcolm’s notes. These notes are valuable for both philosophical and scholarly reasons. They give us a glimpse of a sustained exchange between Wittgenstein and a real-life interlocutor; they contain a defence by Wittgenstein of the idea that a word’s use can illuminate its meaning; and they provide evidence of Wittgenstein’s philosophical engagement with the topic of certainty, and with Moore’s thought on it, long before he began to write the notes which make up On Certainty, in 1949. (shrink)

Public surveys conducted in many countries report widespread willingness of individuals to donate a kidney while alive to a family member or close friend, yet thousands suffer and many die each year while waiting for a kidney transplant. Advocates of financial incentive programs or “regulated markets” in kidneys present the problem of the kidney shortage as one of insufficient public motivation to donate, arguing that incentives will increase the number of donors. Others believe the solutions lie—at least in part—in facilitating (...) so-called “altruistic donation;” harnessing the willingness of relatives and friends to donate by addressing the many barriers which serve as disincentives to living donation. Strategies designed to minimize financial barriers to donation and the use of paired kidney exchange programs are increasingly enabling donation, and now, an innovative program designed to address what has been termed “chronologically incompatible donation” is being piloted at the University of California, Los Angeles, and elsewhere in the United States. In this program, a person whose kidney is not currently required for transplantation in a specific recipient may instead donate to the paired exchange program; in return, a commitment is made to the specified recipient that priority access for a living-donor transplant in a paired exchange program will be offered when or if the need arises in the future. We address here potential ethical concerns related to this form of organ “banking” from living donors, and argue that it offers significant benefits without undermining the well-established ethical principles and values currently underpinning living donation programs. (shrink)

The expansion of research on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises important neuroethics and policy questions related to data sharing. However, there has been little empirical research on the perspectives of experts developing these technologies. We conducted semi-structured, open-ended interviews with aDBS researchers regarding their data sharing practices and their perspectives on ethical and policy issues related to sharing. Researchers expressed support for and a commitment to sharing, with most saying that they were either sharing their data (...) or would share in the future and that doing so was important for advancing the field. However, those who are sharing reported a variety of sharing partners, suggesting heterogeneity in sharing practices and lack of the broad sharing that would reflect principles of open science. Researchers described several concerns and barriers related to sharing, including privacy and confidentiality, the usability of shared data by others, ownership and control of data (including potential commercialization), and limited resources for sharing. They also suggested potential solutions to these challenges, including additional safeguards to address privacy issues, standardization and transparency in analysis to address issues of data usability, professional norms and heightened cooperation to address issues of ownership and control, and streamlining of data transmission to address resource limitations. Researchers also offered a range of views on the sensitivity of neural activity data (NAD) and data related to mental health in the context of sharing. These findings are an important input to deliberations by researchers, policymakers, neuroethicists, and other stakeholders as they navigate ethics and policy questions related to aDBS research. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Essai sur le coeur humain, ou Principes naturels de l'education, par M. MorellyDate de l'edition originale: 1745Ce livre est la reproduction fidele d'une oeuvre publiee avant 1920 et fait partie d'une collection de livres reimprimes a la demande editee par Hachette Livre, dans le cadre d'un partenariat avec la Bibliotheque nationale de France, offrant l'opportunite d'acceder a des ouvrages anciens et souvent rares issus des fonds patrimoniaux de la BnF.Les oeuvres faisant partie de cette collection ont ete numerisees par la (...) BnF et sont presentes sur Gallica, sa bibliotheque numerique.En entreprenant de redonner vie a ces ouvrages au travers d'une collection de livres reimprimes a la demande, nous leur donnons la possibilite de rencontrer un public elargi et participons a la transmission de connaissances et de savoirs parfois difficilement accessibles.Nous avons cherche a concilier la reproduction fidele d'un livre ancien a partir de sa version numerisee avec le souci d'un confort de lecture optimal. Nous esperons que les ouvrages de cette nouvelle collection vous apporteront entiere satisfaction.Pour plus d'informations, rendez-vous sur www.hachettebnf.frhttp: //gallica.bnf.fr/ark: /12148/bpt6k95635b. (shrink)

This is the inaugural volume of the Plato Dialogue Project: it offers the first collective study of the Philebus - a high point of philosophical ethics, containing some of Plato's most sophisticated discussions of human happiness. The contributors work through the text, discussing pleasure, knowledge, philosophical method, and the human good.

Realising the societal gains from publicly funded health and medical research requires a model for a reflexive evaluation precedent for the societal impact of research. This research explores UK Research Excellence Framework evaluators’ values and opinions and assessing societal impact, prior to the assessment taking place. Specifically, we discuss the characteristics of two different impact assessment extremes – the “quality-focused” evaluation and “societal impact-focused” evaluation. We show the wide range of evaluator views about impact, and that these views could be (...) conceptually reflected in a range of different positions along a conceptual evaluation scale. We describe the characteristics of these extremes in detail, and discuss the different beliefs evaluators had which could influence where they positioned themselves along the scale. These decisions, we argue, when considered together, form a dominant definition of societal impact that influences the direction of its evaluation by the panel. (shrink)

In a reflective and richly entertaining piece from 1979, Doug Hofstadter playfully imagined a conversation between ‘Achilles’ and an anthill (the eponymous ‘Aunt Hillary’), in which he famously explored many ideas and themes related to cognition and consciousness. For Hofstadter, the anthill is able to carry on a conversation because the ants that compose it play roughly the same role that neurons play in human languaging; unfortunately, Hofstadter’s work is notably short on detail suggesting how this magic might be achieved1. (...) Conversely in this paper - finally reifying Hofstadter’s imagination - we demonstrate how populations of simple ant-like creatures can be organised to solve complex problems; problems that involve the use of forward planning and strategy. Specifically we will demonstrate that populations of such creatures can be configured to play a strategically strong - though tactically weak - game of HeX (a complex strategic game).We subsequently demonstrate how tactical play can be improved by introducing a form of forward planning instantiated via multiple populations of agents; a technique that can be compared to the dynamics of interacting populations of social insects via the concept of meta-population. In this way although, pace Hofstadter, we do not establish that a meta-population of ants could actually hold a conversation with Achilles, we do successfully introduce Aunt Hillary to the complex, seductive charms of HeX. (shrink)

Obsessive-compulsive disorder (OCD) is a deeply enigmatic psychiatric condition associated with immense suffering worldwide. Efficacious therapies for OCD, like exposure and response prevention (ERP) are sometimes poorly tolerated by patients. As many as 25 percent of patients refuse to initiate ERP mainly because they are too anxious to follow exposure procedures. Accordingly, we proposed a simple and tolerable (immersive yet indirect) low-cost technique for treating OCD that we call “multisensory stimulation therapy.” This method involves contaminating a rubber hand during the (...) so-called “rubber hand illusion” (RHI) in which tactile sensations may be perceived as arising from a fake hand. Notably, Jalal and Ramachandran (2015), showed that such fake hand contamination during the RHI provokes powerful disgust reactions in healthy volunteers. In the current study, we explored the therapeutic potential of this novel approach. OCD patients (n = 29) watched as their hidden real hand was being stroked together with a visible fake hand; either synchronously (inducing the RHI) (i.e., the experimental condition; n = 16) or asynchronously (i.e., the control condition; n = 13). After 5 minutes of tactile stimulation, the rubber hand was contaminated with fake feces, simulating conventional exposure therapy. Intriguingly, results suggested sensory assimilation of contamination sensations into the body image via the RHI: patients undergoing synchronous stimulation did not report greater contamination sensations when the fake hand was initially contaminated relative to asynchronous stroking. But contrary to expectations, they did so after the rubber hand had been contaminated for 5 minutes; as assessed via disgust facial expressions (a secondary outcome) and in vivo exposure (upon discontinuing the illusion). Further to our surprise, synchronous and asynchronous stroking induced an equally vivid and fast emerging illusion, which helps explain why both conditions initially (5 minutes after initiating tactile stimulation) provoked contamination reactions of equal magnitude. This study is the first to suggest heightened malleability of body image in OCD. Importantly, it may pave the way for a tolerable technique for the treatment of OCD—highly suitable for poorly resourced and emergency settings, including low-income and developing countries with minimal access to high-tech solutions like virtual reality. (shrink)

The growing practice of returning individual results to research participants has revealed a variety of interpretations of the multiple and sometimes conflicting duties that researchers may owe to participants. One particularly difficult question is the nature and extent of a researcher’s duty to facilitate a participant’s follow-up clinical care by placing research results in the participant’s medical record. The question is especially difficult in the context of genomic research. Some recent genomic research studies — enrolling patients as participants — boldly (...) address the question with protocols dictating that researchers place research results directly into study participants’ existing medical records, without participant consent. Such privileging of researcher judgment over participant choice may be motivated by a desire to discharge a duty that researchers perceive themselves as owing to participants. However, the underlying ethical, professional, legal, and regulatory duties that would compel or justify this action have not been fully explored. (shrink)

Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether (...) these procedures will ever be ethically and socially justifiable. The book also provides background to define the field, and discusses the biological and technological potential for inheritable genetic modification, its limitations, and its connection with gene therapy, cloning, and other reproductive interventions. For scientists, bioethicists, clinicians, counsellors and public commentators, this is an essential contribution to one of the critical debates in current genetics. (shrink)

Este artigo propõe uma leitura conjunta de Facticidade e validade, de Jürgen Habermas, e Crítica dos direitos, de Christoph Menke. Mais do que identificar os regimes de continuidade e ruptura que este texto estabelece em relação àquele, trata-se de compreender o modo como Menke pensa poder corrigir a teria do discurso introduzindo, a um só tempo, uma ontologia do direito e dos direitos subjetivos modernos, e uma reflexão materialista sobre o não-direito. Para tanto, é preciso elucidar duas questões centrais. Em (...) primeiro lugar, deve-se evidenciar as diferenças de abordagem entre Habermas e Menke quanto à reconstrução histórica do sistema de direitos. Em segundo lugar, deve-se elucidar as diferentes concepções de autorreflexão do direito com as quais trabalham os dois autores. Assim, torna-se possível responder afirmativamente à seguinte pergunta: há uma teoria crítica da vontade política? (shrink)

Some preliminary comments Introduction: The EDWs perspective in my article from 2005 and my book from 2008 -/- I. PHYSICS, COGNITIVE NEUROSCIENCE, PHILOSOPHY (‘REBORN DINOSAURS’ ) • (2016) Did Sean Carroll’s ideas (California Institute of Technology, USA) (within the wrong framework, the “universe”) plagiarize my ideas (2002-2010) (within the EDWs framework) on quantum mechanics, the relationship between Einstein relativity and quantum mechanics, life, the mind-brain problem, etc.? • (2016) The unbelievable similarities between Frank Wilczek’s ideas (Nobel Prize in Physics) and (...) my ideas (2002-2008, etc.) (Philosophy of Mind and Quantum Mechanics) • (2017-2019 NEW) Strong similarity between Carlo Rovelli’s ideas (Italy) in three books (2015, 2017) to my ideas (2002-2008) + commentary February 2018! • (2016) Kastner + (2017) R. E. Kastner, Stuart Kauffman, Michael Epperson “Taking Heisenberg’s Potentia Seriously”: Quite similar ideas to my ideas (2008) + • (2017) A trick: Unbelievable similarities between Lee Smolin’s ideas (2017) and my ideas (2002-2008) • (May 2018) ‘Thus spoke Zarathustra!’ - A fairy-tale with Eugen Ionesco and the Idiot about Nothingness -/- II. PHYSICS • (2011) The unbelievable similarities between Radu Ionicioiu (Physics, University of Bucharest, Romania) and Daniel R. Terno’s ideas (Physics, Macquarie University, Sydney, Australia) and my ideas (Quantum Mechanics) • (2013) Côté B. Gilbert (Oontario, Canada) Unbelievalbe similarities • (2015) The strong similarity between Pikovski Igor, Zych Magdalena, Costa Fabio, and Brukner Časlav’s ideas and my ideas (2006-2008) regarding the Schrodinger’s cat’s interactions with its environment (the gravitation of Earth) (both entities being macro-objects) (Quantum Mechanics) • (2015) The strong similarity between Elisabetta Caffau’s ideas (Center for Astronomy at the University of Heidelberg and the Paris Observatory) and my ideas (2011, 2014) regarding the appearance of Big Bang in many places (Cosmology) • (2015) Did Wolfram Schommers (University of Texas at Arlington, USA & Karlsruhe Institute of Technology, Germany) plagiarize my ideas? (Physics) • (2015) Some astrophysicists about "Dark Matter May be 'Another Dimension' - Or Even a Major Galactic Transport System" January 22, 2015 • (2016) The strong similarities between Dylan H. Mahler, Lee Rozema, Kent Fisher, Lydia Vermeyden, Kevin J. Resch, Howard M. Wiseman, and Aephraim Steinberg’s ideas (USA) and my ideas (Quantum Mechanics) • (2016) The unbelievable similarities between Bill Poirier’s ‘Many Interacting Worlds’ and my EDWs (Quantum Mechanics) • (2016 or 2017) Similarities between Adam Frank’s ideas (University of Rochester in New York , USA) (“Minding matter - The closer you look, the more the materialist position in physics appears to rest on shaky metaphysical ground”) and my ideas (2005, 2008) • (2017, 2017) Did Sebastian de Haro (HPS, Cambridge, UK) plagiarize my ideas (2002-2008) • (2017) Unbelievable similarities between Laura Condiotto’s ideas and my ideas (2002-2008) • (2016) The unbelievable similarities between Hugo F. Alrøe and Egon Noe’s (Department of Agroecology, Aarhus University, Denmark) ideas (USA) and my ideas (2002-2008) (Bohr's complementarity extended to ontology) • (2017) The unbelievable similar ideas between Federico Zalamea’s ideas and my ideas • (2018) Unbelievable similarities between Peter J. Lewis’s ideas (2018) and my ideas (2002-2008) • (2018) Timothy Hollowood, ‘Classical from Quantum’, [arXiv:1803.04700v1 [quant-ph] 13 March 2018] • (2018) Mario Hubert and Davide Romano, ‘The Wave-Function as a Multi-Field’ -/- III. COGNITIVE NEUROSCIENCE AND PHILOSOPHY OF MIND • (2011-2014) Did Georg Northoff (Psychoanalysis, Institute of Mental Health) plagiarize my ideas (2002-2008)? • (2011) The unbelievable similarities between Kalina Diego Cosmelli, Legrand Dorothée and Thompson Evan’s ideas (USA) and my ideas (Cognitive Neuroscience) • (2015) Did David Ludwig (Philosophy, University of Amsterdam) plagiarize many of my ideas? (Philosophy (of Mind) • (2016) Did Neil D. Theise (Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, USA) and Kafatos C. Menas (Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA) plagiarize my ideas of Physics and Cognitive Neuroscience and Philosophy (the mind-brain problem, quantum mechanics, etc.) from 2002-2008? • Did David Bourget (2018) (Director, Centre for Digital Philosophy, Western University (or University of Western Ontario) plagiarize my ideas regarding the mind-brain problem? + Chalmers • (2016) Unbelievable similarities between Dan Siegel’s ideas (Mindsight Institute, USA) and my ideas (2002-2008) -/- IV. Philosophy (of science) • (2010) The unbelievable similarities between Alexey Alyushin (Moscow, Russia) and my ideas (on Ontology) • (2013 + 2017) Did Markus Gabriel (Bonn University) plagiarize my ideas? • (2013) The unbelievable similarities between Andrew Newman’s ideas (University of Nebraska, at Omaha, USA) and my ideas (Ontology) • (2016) Did Tahko E. Tuomas (University of Helsinki, Finland) plagiarize my ideas? + Tahko E. Tuomas (‘The Epistemology of Essence’) • (2017) Did Jani Hakkarainen (University of Tampere, Finland) plagiarize my ideas (2002-2008)? + (2017) Markku Keinänen, Antti Keskinen & Jani Hakkarainen • (2017) The unbelievable similarities between Dean Rickles’s ideas (HPS, Univ. of Sydney) and my ideas (2002-2008) • (2017) Did Dirk K. F. Meijer and Hans J. H. Geesink (University of Groningen, Netherlands) plagiarize my ideas (2002-2008)? (2017) • (2018) Unbelievable similar ideas between Jason Winning’s ideas (2018) and my ideas (2002-2008) • (2018) David Mark Kovacs (Lecturer of philosophy at Tel Aviv University), ‘The Deflationary Theory of Ontological Dependence’, Philosophical Quarterly (forthcoming) -/- Conclusion [Obviously, there are other “specialists” that published UNBELIEVABLE similar ideas to my ideas but I have not discovered them yet…] Bibliography [Some people haven't read my works but they claim my ideas can be found in other works. Soon, they will discover EDWs in Shakespeare, Bach, Sophocles and ET's letter sent 10 million years ago... me vs. people who have plagiarized my ideas: on Youtube] ------------------------------------------------------------------ July 2018 -/- • Oreste M. Fiocco • Baptiste Le Bihan (University of Geneva, forthcoming) • Antonella Mallozzi (The Graduate Center – CUNY, forthcoming in Synthese, penultimate draft) • Erik C. Banks (Wright State University, 2014) • Sami Pihlström (2009) • Katherin Koslicki’s ideas (2008) The Structure of Objects, Oxford University Press) and my ideas (2002-2005-2006) -/- November 2018 • Maurizio Ferraris (2014/2012) Manifesto of New Realism -/- • Graham Harman (2017) : Object-Oriented Ontology: A New Theory of Everything (Penguin Books) ---------------------------------------------------------------- -/- January 2019 • Philip Ball (2018): “Why everything you thought you knew about quantum physics is different” • Gerhard Grössing “Vacuum landscaping: cause of nonlocal influences without signaling” • Anne Sophie Meincke (November 2018) The Disappearance of Change (IJPS) 28. The Disappearance of Change Towards a Process Account of Persistence Forthcoming in: International Journal of Philosophical Studies DOI: 10.1080/09672559.2018.1548634 • Baptiste Le Bihana (University of Geneva) and James Read (Oxford Univ.) “Duality and Ontology” (forthcoming, in Philosophy Compass) • Baptiste Le Bihan (University of Geneva): “Space Emergence in Contemporary Physics: Why We Do Not Need Fundamentality, Layers of Reality and Emergence” in Disputatio, Vol. X, No. 49, November 2018 • Alexander Alexandrovich Antonov (2016) (Research Center of Information Technologies “TELAN Electronics”, Kiev, Ukraine): “Hypothesis of the Hidden Multiverse Explains Dark Matter and Dark Energy”, Journal of Modern Physics, 2016, 7, 1228-1246 -/- February 2019 • James Barham (2019): “The Reality of Purpose and the Reform of Naturalism” • Giorgio Lando (2017) Mereology - A Philosophical Introduction, Bloomsbury Academic • (2018) Albrecht von M¨uller • Elias Zafiris, Concept and Formalization of Constellatory Self-Unfolding - A Novel Perspective on the Relation between Quantum and Relativistic Physics • (2019) Flaminia Giacomini, Esteban Castro-Ruiz, & Časlav Brukner “Quantum mechanics and the covariance of physical laws in quantum reference frames”, Nature Communications • (2019) Valia Allori, “Scientific Realism without the Wave-Function: An Example of Naturalized Quantum Metaphysics” (to appear in J. Saatsi, S. French (eds.) “Scientific Realism and the Quantum” OUP (2019) - Department of Philosophy Northern Illinois University) • (2018) Paulo De Jesus “Thinking through enactive agency: sense-making, bio-semiosis and the ontologies of organismic worlds”, Phenom Cogn Sci • (2016) TIMOTHY MORTON, For a Logic of Future Coexistence, (Columbia University Press) • (2017) Andrew Cooper, Two directions for teleology: naturalism and idealism, Synthese . (shrink)

The growing practice of returning individual results to research participants has revealed a variety of interpretations of the multiple and sometimes conflicting duties that researchers may owe to participants. One particularly difficult question is the nature and extent of a researcher’s duty to facilitate a participant’s follow-up clinical care by placing research results in the participant’s medical record. The question is especially difficult in the context of genomic research. Some recent genomic research studies — enrolling patients as participants — boldly (...) address the question with protocols dictating that researchers place research results directly into study participants’ existing medical records, without participant consent. Such privileging of researcher judgment over participant choice may be motivated by a desire to discharge a duty that researchers perceive themselves as owing to participants. However, the underlying ethical, professional, legal, and regulatory duties that would compel or justify this action have not been fully explored. (shrink)